Review





Similar Products

nucview 405 caspase 3 7 substrate  (Biotium)
95
Biotium nucview 405 caspase 3 7 substrate
Nucview 405 Caspase 3 7 Substrate, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pm42092133-651-10-14?v=Biotium
Average 95 stars, based on 1 article reviews
nucview 405 caspase 3 7 substrate - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
nucview 488 caspase 3 substrate  (Biotium)
95
Biotium nucview 488 caspase 3 substrate
Nucview 488 Caspase 3 Substrate, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/us12616715-231-24-29?v=Biotium
Average 95 stars, based on 1 article reviews
nucview 488 caspase 3 substrate - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
nucview caspase 3 enzyme substrates  (Biotium)
95
Biotium nucview caspase 3 enzyme substrates
Nucview Caspase 3 Enzyme Substrates, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pmc13111737-291-13-17?v=Biotium
Average 95 stars, based on 1 article reviews
nucview caspase 3 enzyme substrates - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
nucview 488 caspase  (Biotium)
95
Biotium nucview 488 caspase
A significant activation of <t>caspase-3/7</t> was observed after treating CEM cells for 5 h with compound 22 .
Nucview 488 Caspase, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pmc13139020-193-9-14?v=Biotium
Average 95 stars, based on 1 article reviews
nucview 488 caspase - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
caspase  (Biotium)
95
Biotium caspase
A significant activation of <t>caspase-3/7</t> was observed after treating CEM cells for 5 h with compound 22 .
Caspase, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/10__1172_slash_jci199838-266-3-10?v=Biotium
Average 95 stars, based on 1 article reviews
caspase - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
nucview 488 caspase 3 enzyme substrate  (Biotium)
95
Biotium nucview 488 caspase 3 enzyme substrate
(A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and <t>NucView</t> <t>488</t> <t>Caspase-3</t> substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.
Nucview 488 Caspase 3 Enzyme Substrate, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/bio_rxiv__64898__2026__04__05__716056-49-4-11?v=Biotium
Average 95 stars, based on 1 article reviews
nucview 488 caspase 3 enzyme substrate - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
dab substrate kit  (Cell Signaling Technology Inc)
93
Cell Signaling Technology Inc dab substrate kit
(A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and <t>NucView</t> <t>488</t> <t>Caspase-3</t> substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.
Dab Substrate Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pm41896941-96-22-25?v=Cell+Signaling+Technology+Inc
Average 93 stars, based on 1 article reviews
dab substrate kit - by Bioz Stars, 2026-08
93/100 stars
  Buy from Supplier
nucview 488 substrate  (Biotium)
95
Biotium nucview 488 substrate
(A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and <t>NucView</t> <t>488</t> <t>Caspase-3</t> substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.
Nucview 488 Substrate, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pm41841523-89-5-10?v=Biotium
Average 95 stars, based on 1 article reviews
nucview 488 substrate - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
nucview caspase 3 substrates  (Biotium)
95
Biotium nucview caspase 3 substrates
(A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and <t>NucView</t> <t>488</t> <t>Caspase-3</t> substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.
Nucview Caspase 3 Substrates, supplied by Biotium, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caspase+3+substrate/pm41786693-228-0-3?v=Biotium
Average 95 stars, based on 1 article reviews
nucview caspase 3 substrates - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier

Image Search Results


A significant activation of caspase-3/7 was observed after treating CEM cells for 5 h with compound 22 .

Journal: Frontiers in Pharmacology

Article Title: A novel quinine derivative as a PIM-1 kinase inhibitor induces apoptosis via mitochondrial depolarization with selective cytotoxicity in acute lymphoblastic leukemia cells

doi: 10.3389/fphar.2026.1799674

Figure Lengend Snippet: A significant activation of caspase-3/7 was observed after treating CEM cells for 5 h with compound 22 .

Article Snippet: Caspase-3/7 activation was assessed in CEM cells using the NucView 488 caspase-3 fluorogenic substrate (Biotium, #10402, Fremont, USA).

Techniques: Activation Assay

(A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and NucView 488 Caspase-3 substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.

Journal: bioRxiv

Article Title: Synergistic induction of a lethal Autosis-to-Apoptosis switch by Phytocannabinoids and beta-Caryophyllene in Triple-Negative Breast Cancer Cells

doi: 10.64898/2026.04.05.716056

Figure Lengend Snippet: (A) MDA-MB-231 cells were treated with vehicle (0.3% DMSO - Control) or combinations C1 to C3 as described in in the presence of SYTOX Green and SPY-DNA. Automated live-cell imaging was performed for 72h and representative composite images combining the phase contrast, green (SYTOX Green, dead cells), and NiR (SPY650-DNA, nuclei) fluorescence channels obtained at different time points are displayed. Dead cells (SPY + /SYTOX Green + nuclei) are indicated by white arrows. Insets show higher magnifications of specific elements. Blue boxes highlight retracted cells exhibiting cytoplasmic vacuoles, yellow boxes indicate cells displaying extensive cytoplasmic blebbing, and orange boxes highlight the formation of large cytoplasmic blisters (orange arrows) characteristic of secondary necrosis. Scale bar corresponds to 200 µm. See Videos S1-4 (Supplementary Material) for the complete 72 h time-lapse sequences. (B) MDA-MB-231 cells were treated with combinations C1 in the presence of SYTOX Orange and NucView 488 Caspase-3 substrate. Automated live-cell imaging was performed and representative phase contrast and composite images combining the green (NucView, active caspase-3) and orange (SYTOX Orange, dead cells) fluorescence channels obtained at different time points are displayed. Retracted cells are indicated by white arrow heads.

Article Snippet: To evaluate apoptosis, the NucView® 488 Caspase-3 enzyme substrate (0.5 μM; Biotium, USA) was used, with staurosporine (0.5 μM) as a specific positive control for caspase activation.

Techniques: Control, Live Cell Imaging, Fluorescence